Ok, here's the ad I had originally found. It does suggest there are certain types deemed "sensitive" that should be removed.....
Chelated copper treatment recommended for the treatment of ick, flukes, anchor worms, velvet, protozoan diseases and other external parasites.
Benefit: CopperSafe is a chelated copper compound that is used for the treatment of infections of : Ick, Flukes (Gyrodactylus), Anchor Worms, Velvet/Protozoan diseases and other external parasites. CopperSafe when used as directed maintains a total copper level of 1.5 ppm to 2.0 ppm in the water. CopperSafe remains active for over one month in the aquarium. Levels of 0.3 ppm free copper are recommended in the literature for therapeutic use but with Coppersafe the levels of free copper will be measured at 1.5 ppm to 2.0 ppm. This level of copper can be used in the treatment of fish due to Coppersafe's unique chelating agent. The chelating agent binds with the copper making it nontoxic to fish but effective against parasites. CopperSafe does not color the water and will not interfere with the biological filter
Use: CopperSafe should be used when a diagnosis of the fishes illness indicates the presence of Ick, Flukes (Gyrodactylus), Anchor Worms, Velvet/ Protozoan Diseases and other external freshwater parasites. CopperSafe may cause an adverse reaction with some sensitive invertebrates. Invertebrates without an exoskeleton such as jellyfish and anemones should be removed before treatment. CopperSafe may be harmful to plants, amphibians and snails. A chelated or total copper test kit is required to measure CopperSafe. Coppersafe may cause inaccurate free copper readings when using certain test kits. All readings should be based on the total copper or chelated copper results and not the free copper results.Coppersafe is safe to use with U.V. Sterilizers, Protein Skimmers, Wet/Dry and Diatomaceous earth filters. After treatment Coppersafe can be removed from the aquarium by water changes, fresh activated carbon or other chemical filtration resins/pads. For use in both fresh and saltwater tanks.
Active Ingredients: Chelated Copper sulfate